UCLAB Stem Cell

What is

Clinical Grade

Our established technology platform enables us to produce clinical "ready-made" human umbilical cord mesenchymal stem cells from umbilical cord tissues. Compared with stem cells derived from other adult tissues, our mesenchymal stem cells have strong advantages, including non-invasive operation on donors, strong proliferation, super scalability in vitro and excellent biological activity. We also have the proprietary technology to change hUC-MSC by chemical or genetic means to expand its application scope. Our mesenchymal stem cells have unique anti-aging, anti-wrinkle , and youthful functions, which are unmatched by other treatments.

9 Features

of clinical grade

Tests per FDA Criteria

Effective IND

cGMP Lab

High Purity

High Viability

High Biological Potency

Fresh Cell Suspension

Donor Screenings

Standard Stem Cell Bank

Robusts

Cells in Culturing

UCLAB MSCs were represented at different confluences under microscope

High Purity 95%

According to the minimal criteria to define human MSCs by ISCT, MSCs must express CD105, CD90, and CD73 and be lack expression of CD45, CD34, CD11β, CD19, and HLA-DR. The purity of UCLAB MSC products is far above the FDA acceptance criteria.

CD Makers Expession Level	FDA Criteria	UCLAB MSCs
CD105(+)	≥ 95%	99.92%
CD90(+)	≥ 95%	100%
CD73(+)	≥ 95%	99.96%
CD45(-)	≤ 2%	0.21%
CD34(-)	≤ 2%	0.01%
HLA-DR(-)	≤ 2%	0.19%
CD11ß	≤ 2%	0.49%
CD19	≤ 2%	0.11%

High Viability 90%

With patented technology of in-vitro cell culturing and expansion, UCLAB products are recognized as the top-tier mesenchymal stem cells in the world with extremely high viability and vitality above FDA criteria.

	FDA Criteria	UCLAB MSCs
Viability	≥ 90%	98.41%

Multilineage

Differentiation

Based on ISCT's minimal criteria, MSCs must differentiate into osteoblasts, adipocytes, and chondroblasts in virtro. The pictures below are Osteogenic and Adipogenic differentiations from UCLAB MSC products.

Osteobalsts

Adipocytes

Screenings of donors

Test Item	Test Method	Acceptance Criteria	Test Result
HIV I	Anti-HIV1	Negative	Negative
HIV II	Anti-HIV2	Negative	Negative
HBV	HBsAg	Negative	Negative
HBV	Anti-HBc	Negative	Negative
HCV	Anti-HCV	Negative	Negative
HTLV-I	Anti-HTLV-I	Negative	Negative
HTVL-II	Anti-HTLV-II	Negative	Negative
TP	TP antibodies	Negative	Negative
WNV	NAT	Negative	Negative
Chlamydia Trachomatis	NAT	Negative	Negative
Neisseria Gonorrhea	NAT	Negative	Negative
CMV	Anti-CMV lgG/1gM	For record only	For record only

Screening Item	Acceptance Criteria
Zika virus	No History
CJD	No History
Sepsis	No History
HTLV	No History
Vaccinia	No History
WNV	No History
Chlamydia Trachomatis	No History
Neisseria Gonorrhea	No History
Malignancy	No History
Gestational Hyperglycemia	No History
Diabetes	No History
Hypertension	No History